31 Jan 2023 --- Researchers from the University of California Riverside (UCR), US, found that fathers exposed to chemicals in plastics can affect the metabolic health of their offspring for two generations.The researchers used mice as test subjects to find that paternal dicyclohexyl phthalate (DCHP) exposure for four weeks led to high insulin resistance and impaired insulin signaling in F1 (first) offspring. The same but weaker effect was seen in F2 (second generation) offspring.